Gene Variants Predict Breast Cancer

Rosa and Alex Dembitzer - Northern Charitable Foundation - Breast cancer genetic research

Tumor development and the role of hereditary factors are highly correlated. A new class of biomarkers forecasts tumor progression and an entirely new way of understanding breast cancer origins. The gene sequences we inherit at conception can predict the type and severity of breast cancer we could develop decades later. The active involvement of gene … Read more

New Research: Preventative Mastectomies and Reducing Breast Cancer Risk 

New research from Canada shows that preventive mastectomies can reduce the risks of breast cancer in women with certain forms of BRCA genes that, without intervention, significantly increase the risk of breast cancer. Mutations Raise Risk Every human has both the BRCA1 and BRCA2 genes. However, sometimes these genes become damaged or change in some … Read more

Awareness for Male Breast Cancer – Don’t Leave it Too Late

male cancer

Breast cancer is the second most common cancer among women in the US, yet it is also possible for men to be diagnosed too. Although males receive only up to 1% of all breast cancer diagnoses, it is usually diagnosed at later, harder-to-treat stages, leading to approximately 500 men dying from it each year in … Read more

Hereditary Cancers Don’t Only Affect Women: BRCA2 Mutation Can Also Affect Ashkenazi Men

With the discovery of the BRCA2 gene in December 1995, researchers have been able to gain valuable insights and a better understanding of the role it plays in terms of the development of cancer. We inherit two copies of the BRCA2 gene in every one of our cells, one from our father and one from … Read more

Hereditary Cancers Don’t Only Affect Women: BRCA2 Mutation Can Also Affect Ashkenazi Men

Northern Charitable Foundation - genetic cancers in men

With the discovery of the BRCA gene in December 1995, researchers have been able to gain valuable insights and a better understanding of the role it plays in terms of the development of cancer. We inherit two copies of the BRCA gene in every one of our cells, one from our father and one from … Read more

Genes and Mutations: Understanding BRC1 and BRC2

Alex and Rosa Dembitzer - Northern Charitable Foundation - understanding BRCA gene mutations

All women are at risk of developing breast cancer during their lifetime. There are various risk factors that can increase the likelihood, one of them being genetic susceptibility. Genes are segments of DNA (deoxyribonucleic acid), and DNA makes up chromosomes. Humans have 23 pairs of chromosomes, receiving half of each pair from the mother and … Read more

The Signs of Ovarian Cancer: Know What to Look For

Dembitzer - Northern Charitable Foundation - the sings of ovarian cancer

Cancer, a word everyone is familiar with, is a term for diseases that can affect any part of the body. These diseases are caused by the rapid, abnormal growth of cells that have the potential to extend beyond their normal boundaries into other parts of the body and organs. When diagnosed and treated in the … Read more

What Is Triple-Negative Breast Cancer and How Does It Relate To The BRCA Gene Mutation?

Northern Charitable Foundation - Rosa and Alex Dembitzer - Breast cancer information

Triple-Negative Breast Cancer (TNBC) is an aggressive form of breast cancer which spreads and grows rapidly in the body. Approximately 10-15% of all breast cancers are TNCB, named triple-negative for its negative testing of three molecular components – estrogen, progesterone, and human epidermal growth factor (HER2). This cancer is more likely to return than other … Read more

Why The Northern Charitable Foundation Sponsors the Prevention GENEration Program

Rosa Dembitzer - Breast cancer awareness month

We are very passionate about sponsoring the Israel Cancer Association’s Prevention GENEration Program in collaboration with The Israel Hereditary Breast and Ovarian Cancer Consortium. The aim of the program is to reduce cancer morbidity in Israel by promoting research, prevention, early detection, treatment modalities, and means of rehabilitation. The High Rate of Individuals with the … Read more

New Parp Inhibitor Lynparza May Be Important Tool for Treating Early-Stage Breast Cancer

Northern Charitable Foundation - breast cancer research

The President of the American Society for Clinical Oncology shared that new research has found that the Lynparza parp inhibitor could have a significant impact on the treatment and decision paths of patients with both high-risk and early-stage breast cancer. The study also showed that Lynparza reduces the chances that patients with the BRCA gene … Read more